Titelbild: Organocatalytic Enantioselective Synthesis of Axially Chiral <i>N</i>,<i>N′</i>‐Bisindoles (Angew. Chem. 15/2023)

نویسندگان

چکیده

An axially chiral N,N′-bisindole is shown on the cover picture, representing one of fruits tree indole chemistry. In their Research Article (e202300419), Yu-Chen Zhang, Feng Shi, and co-workers describe organocatalytic enantioselective construction scaffold with promising applications in medicinal chemistry asymmetric catalysis. Aptamers Carbon Dioxide Capture Batteries Photocatalysis

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Organocatalytic atroposelective synthesis of axially chiral styrenes

Axially chiral compounds are widespread in biologically active compounds and are useful chiral ligands or organocatalysts in asymmetric catalysis. It is well-known that styrenes are one of the most abundant and principal feedstocks and thus represent excellent prospective building blocks for chemical synthesis. Driven by the development of atroposelective synthesis of axially chiral styrene der...

متن کامل

Enantioselective organocatalytic Hantzsch synthesis of polyhydroquinolines.

The four-component Hantzsch reaction provides access to pharmaceutically important dihydropyridines. To expand the utility of this method, we have developed a route under organocatalytic conditions with good yields and excellent ee's. Through catalyst screening, we found that a BINOL-phosphoric acid allowed enantioselective synthesis of six-membered heterocycles with a variety of substitution p...

متن کامل

Organocatalytic enantioselective synthesis of 2,3-dihydropyridazines.

We have developed an efficient procedure for the easy and straightforward preparation of functionalized dihydropyridazines as highly enantiopure materials by reaction of pyruvaldehyde 2-tosyl hydrazone with a variety of α,β-unsaturated aldehydes using a chiral secondary amine as catalyst. The overall process consists of a cascade reaction involving an initial aza-Michael reaction, in which the ...

متن کامل

An efficient organocatalytic enantioselective synthesis of spironitrocyclopropanes.

An organocatalytic asymmetric synthesis of spironitrocyclopropanes has been demonstrated starting from 2-arylidene-1,3-indandiones and bromonitroalkanes catalyzed by a cinchona-derived bifunctional organocatalyst. The products were obtained with excellent enantioselectivities, diastereoselectivities and with good yields.

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Angewandte Chemie

سال: 2023

ISSN: ['1521-3773', '1433-7851', '0570-0833']

DOI: https://doi.org/10.1002/ange.202303144